Treatment of schizophrenia in adult & adolescents ≥15 yr. Treatment of manic episodes in bipolar I disorder in adult & adolescents ≥13 yr. Prevention of manic episodes in adult patients who have responded to aripiprazole treatment.
High blood sugar or family history of diabetes; seizure; involuntary, irregular muscle movements, especially in the face; CV diseases, family history of CV disease, stroke or 'mini' stroke, abnormal BP; blood clots or family history of blood clots; past experience of excessive gambling. Elderly patients suffering from dementia. Suicidal thoughts & behaviours. Consult physician in case of wt gain, development of unusual movements, somnolence, difficulty in swallowing, allergic symptoms; muscle stiffness or inflexibility w/ high fever, sweating, altered mental status, or very rapid or irregular heartbeat. Do not drive or use any tools or machines until effect of Aryzalera is known. Intolerance to some sugars. Pregnancy & lactation. Not for use in childn & adolescent <13 yr.
Uncontrollable twitching or jerking movements, headache, tiredness, nausea, vomiting, uncomfortable feeling in the stomach, constipation, increased production of saliva, light-headedness, trouble sleeping, restlessness, feeling anxious, sleepiness, shaking, blurred vision.
Drug Interactions
Antiarrhythmics, antidepressants or herbal remedy for depression & anxiety, antifungal agents, certain HIV medicines, anticonvulsants. Increased effect of BP-lowering medicines. Increased risk of side effects w/ triptans, tramadol, tryptophan, SSRIs (eg, paroxetine and fluoxetine), tricyclics (eg, clomipramine, amitriptyline), pethidine, St John's wort, venlafaxine.
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