Experience with overdose of dasatinib in clinical studies is limited to isolated cases. The highest reported dosage ingested was 280 mg per day for 1 week in two patients and both developed a significant decrease in platelet counts. Since dasatinib is associated with severe myelosuppression (see Precautions and Adverse Reactions), patients who ingested more than the recommended dosage should be closely monitored for myelosuppression and appropriate supportive treatment given.