Amitriptyline Actavis Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Stop taking Amitriptyline tablets and contact the doctor at once if the patient has: An allergic reaction signs may include a skin rash, which may be itchy, sensitivity to the sun or sun lamps, puffy, swollen face or tongue, which may be severe causing shortness of breath, swelling, shock and collapse.
A serious effect on the blood, such as low sodium levels. Signs may include fever or chills, sore throat, ulcers in the mouth or throat, unusual tiredness or weakness, unusual bleeding or unexplained bruises.
Bone marrow depression or reduction in some blood cells (the patient may experience a sore throat, mouth ulcers and recurring infections, bleeding or bruising easily); thoughts of suicide (see Actions and Indications); anticholinergic effects (dry mouth, fever, constipation, blurred or double vision, difficulty or lack of control when urinating, dilation of the pupil of the eye, glaucoma and blockage of the small intestine); stroke; hepatitis.
Tell the doctor if the patient notices any of the following side effects or notices any other effects not listed: Common (may affect up to 1 in 10 people): A heart problem called prolonged QT interval (which is shown on the electrocardiogram, ECG).
Not known (frequency cannot be estimated from the available data): Rash of purple spots (purpura).
Disturbances in sexual function or sex drive, breast swelling in men and women, swelling of the testicles, production or over-production of breast milk, changes in blood sugar levels, increased appetite and weight gain. Inappropriate secretion of the hormone ADH (antidiuretic hormone), which may make the patient urinate more frequently.
Dizziness, tiredness or sleepiness, weakness, headache, difficulty concentrating, confusion, difficulty sleeping, nightmares, slight hyperactivity, exaggerated behaviour, delusions, seeing things that are not there, anxiety, excitement, disorientation (not knowing where he/she is), restlessness, nerve damage, pins and needles, lack of co-ordination, loss of control of or shaky movements, tremor, fits.
Feeling faint when getting up (postural hypotension), increased blood pressure, fast/ racing heart, palpitations, heart attack, irregular or slow heart-beats and very low blood pressure, other changes in ECGs.
Feeling or being sick, diarrhoea, loss of appetite, inflammation of the mucus membranes in the mouth, swollen saliva glands, abdominal pains, black tongue, impairment of taste.
Including changes in liver function (as seen in blood tests), jaundice (yellowing of the skin and/or whites of the eyes).
Increased sweating, hair loss, ringing in the ears, increased need to urinate. An increased risk of bone fractures has been observed in patients taking this type of medicine.
Withdrawal symptoms: Feeling sick, malaise and headache, dream and sleep disturbances, irritability and restlessness. Mania or hypomania (exaggerated mood and/or elation) may occur 2-7 days after stopping the tablets.
If taken to treat bed-wetting: drowsiness, mild sweating, itching, changes in behaviour and "Anticholinergic effects" (as described previously).
Reporting of side effects: If the patient gets any side effects, talk to the doctor, pharmacist or nurse. This includes any possible side effects not listed. The patient can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.
By reporting side effects the patient can help provide more information on the safety of the medicine.