Alonet Dosage/Direction for Use

Adults: To be taken orally.
Hypertension: 50-100 mg tablet daily. Most patients respond to 100 mg daily given orally as a single dose. Some patients, however, will respond to 50 mg given as a single daily dose. The effect will be fully established after one to two weeks.
Angina pectoris: Most patients with angina pectoris will respond to 100 mg given orally once daily or 50 mg given twice daily. It is unlikely that additional benefit will be gained by increasing the dose.
Elderly: Dosage requirements may be reduced, especially in patients with impaired renal function.
Renal impairment: Since atenolol tablets are excreted via the kidneys, the dosage should be adjusted in cases of severe impairment of renal function.
No significant accumulation of atenolol occurs in patients who have a creatinine clearance greater than 35 ml/min/1.73 m².
For patients with a creatinine clearance of 15-35 ml/min/1.73 m², the oral dose should be 50 mg daily.
For patients with a creatinine clearance of less than 15 ml/min/1.73 m² (equivalent to serum creatinine of greater than 600 micromol/litre), the oral dose should be 25 mg daily or 50 mg on alternate days.