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Each vial contains 50 mg of brentuximab vedotin.
After reconstitution (see Special precautions for disposal and other handling under Cautions for Usage), each mL contains 5 mg of brentuximab vedotin.
ADCETRIS is an antibody-drug conjugate composed of a CD30-directed monoclonal antibody (recombinant chimeric immunoglobulin G1 [IgG1], produced by recombinant DNA technology in Chinese Hamster ovary cells) that is covalently linked to the antimicrotubule agent monomethyl auristatin E (MMAE).
Excipient with known effect: Each vial contains approximately 13.2 mg of sodium.
Excipients/Inactive Ingredients: Citric acid monohydrate (for pH-adjustment), Sodium citrate dihydrate (for pH-adjustment), α,α-Trehalose dihydrate, Polysorbate 80.
