Schizophrenia Adult 10 or 15 mg/day, may be increased at intervals of not <2 wk.
Adolescent 13-17 yr Initially 2 mg/day, titrated to 5 mg/day after 2 days & to the target dose of 10 mg/day after 2 additional days. Subsequent dose increases should be administered in 5-mg/day increment. Max: 30 mg/day.
Bipolar disorder Adult Monotherapy: Initially 15 mg. Adjunctive therapy: 10-15 mg w/ lithium or valproate. Maintenance: Same dose needed to stabilize patients during acute treatment.
Childn 10-17 yr Initially 2 mg/day, titrated to 5 mg/day after 2 days & to the target dose of 10 mg/day after 2 additional days. Subsequent dose increases should be administered in 5-mg/day increment. Max: 30 mg/day.
Adjunctive treatment of major depressive disorder Adult Initially 2-5 mg/day. Dose range: 2-15 mg/day. Gradually adjust dose up to 5 mg/day at intervals of not <1 wk.
Irritability associated w/ autistic disorder Childn 6-17 yr Initially 2 mg/day, may be increased to 10-15 mg/day. Gradually adjust dose up to 5 mg/day at intervals of not <1 wk.
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