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Youth-onset T2D patients at high risk of CVD, ESKD
The risks of cardiovascular disease (CVD) and end-stage kidney disease (ESKD) are elevated twofold in individuals with youth-onset type 2 diabetes (T2D), which is partly caused by the greater burden of obesity and other metabolic risk factors in this population, relative to those with type 1 diabetes (T1D), according to a Hong Kong study.
Android fat deposition tied to increased NAFLD, fibrosis prevalence in women
An android fat deposition pattern, independent of body mass index (BMI), appears to predict higher odds of nonalcoholic fatty liver disease (NAFLD) in both men and women, but its effect on fibrosis is only seen in females, suggests a US study.
Novel genetic element ties valine metabolism to heart failure in T2D
A new study presented at the recent 2022 Scientific Sessions of the American Diabetes Association (ADA 2022) has identified a novel genetic locus associated with heart failure (HF) risk among patients with type 2 diabetes (T2D). This locus appears to play a role in the metabolism of valine, a branched chain amino acid.
Ixa-dex, pom-dex both effective in heavily pretreated relapsed, refractory multiple myeloma
Ixazomib-dexamethasone (ixa-dex) and pomalidomide-dexamethasone (pom-dex) achieve comparable levels of efficacy and safety in relapsed and refractory multiple myeloma (RRMM) patients who had already been exposed to prior lenalidomide-based regimens, a recent study has found.