Tin tức & Cập nhật

Individuals with overweight or obesity in East Asia shed more weight following treatment with the fixed-dose combination of cagrilintide plus semaglutide than with semaglutide alone, as shown in the phase 3a REDEFINE 5 trial.

The use of angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers (ACEi/ARB) appears to reduce the risk of all-cause mortality and major adverse kidney events (MAKE) in very old adults who underwent dialysis for acute kidney injury (AKI), suggests a study.

Combination treatment with zibotentan and dapagliflozin results in a favourable safety profile and good tolerability in patients with compensated cirrhosis, but its effect on hepatic venous pressure gradient (HVPG) is inconclusive, a study has shown.

First-time seizures appear to be associated with increased short-term and long-term risks of cancer, according to a population-based cohort study.

In patients with intrahepatic cholangiocarcinoma (ICC), tumour multiplicity – particularly the presence of ≥4 tumours – is associated with inferior overall survival (OS), a study conducted in Hong Kong, Seoul and Shanghai has shown.

The thrombopoietin-receptor agonist romiplostim helps mitigate chemotherapy-induced thrombocytopenia, reducing related treatment modifications in patients with gastrointestinal cancers, as shown in the landmark phase III RECITE trial.

The presence of a colonic anastomosis during colon conduit urinary diversion (CCUD) does not appear to result in poor outcomes within 30 days, according to a study. However, hypoalbuminemia may contribute to a higher likelihood of 30- to 90-day high-grade complications.

Varicocelectomy in adolescent boys with varicocele results in improved testicular growth and higher spermatogenesis measures into adulthood, suggests a study.