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Investigational nasal spray for dry eye disease scores high in phase II trial
The single-dose nicotinic acetylcholine receptor agonist OC-02, administered as an aqueous nasal spray, helps increase tear production and improve eye dryness in patients with dry eye disease (DED), according to data from the phase II PEARL trial.

How effective is ensovibep in hospitalized adults with COVID-19?
Hospitalized patients with COVID-19 who are receiving remdesivir and other standard care show no improvements in clinical outcomes with the addition of ensovibep, according to the results of a study.

Does TB influence viral suppression in HIV patients on DTG-based therapy?
Incident tuberculosis (TB) appears to be a risk factor for virologic non-suppression (ie, viral load of >1,000 copies/mL) in HIV patients who have transitioned to dolutegravir (DTG)-based therapy with recycled NRTIs*, according to a retrospective subanalysis of the VISEND study.

Exercise during childhood, adolescence improves diastolic function in HCM
Children and teens who engage in more physical exercise are more likely to have favourable left ventricular (LV) diastolic function in hypertrophic cardiomyopathy (HCM), regardless of the presence of hypertrophy at the time of assessment, reports a recent study.




