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Deucravacitinib bests placebo, apremilast in moderate-to-severe plaque psoriasis
Treatment with deucravacitinib achieves better efficacy than placebo and apremilast in patients with moderate-to-severe plaque psoriasis, while also yielding a good safety profile, reports a recent study.

Absence of standard modifiable cardiovascular risk factors tied to poor outcomes in type 2 AMI
Among patients with type 2 acute myocardial infarction (AMI), the absence of standard modifiable cardiovascular risk factors (SMuRF) appears to worsen poor outcomes, such as mortality, stroke, and major adverse cardiovascular and cerebrovascular events (MACCE), a new study has found.

AF increases susceptibility to stroke associated with air pollution exposure
Atrial fibrillation (AF) exacerbates the effect of air pollution exposure on acute ischaemic stroke outcomes, such that AF patients are more likely to develop stroke when exposed to increasing levels of smog (O3) and carbon monoxide (CO) compared with those who have no AF, according to a Singapore study.

Transcutaneous electrical acustimulation effective in IBS with constipation
Patients with irritable bowel syndrome (IBS) and constipation (IBS-C) can improve their symptoms by undergoing transcutaneous electrical acustimulation (TEA), suggests a study. TEA speeds up colon transit and reduces rectal sensation, which is potentially mediated by using the autonomic mechanisms.




