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1-year mortality elevated after procedural/spontaneous myocardial infarction
A significantly higher 1-year mortality is seen following procedural myocardial infarction (pMI) and spontaneous MI (spMI) with troponin peak >35x the upper reference level (URL), reports a study. On the other hand, only spMI demonstrates a significant influence on mortality for troponin levels ≤35x.
CLD status does not influence MACE risk associated with ticagrelor vs clopidogrel
Use of ticagrelor compared with clopidogrel contributes to a similar risk of major adverse cardiovascular events (MACE) and a higher risk of major bleeding in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI), reveals a study.
Prior MI or stroke may predict diuretic use for HTN management
A prespecified secondary analysis of the Diuretic Comparison Project (DCP) shows that when deciding between chlorthalidone (CTD) and hydrochlorothiazide (HCTZ) for the management of hypertension (HTN), a history of myocardial infarction (MI) or stroke may have to be considered.
Nearly half of dementia cases preventable by tackling 14 risk factors
Nearly half of dementia cases could be prevented or delayed by addressing 14 modifiable risk factors starting from childhood, including two new risk factors – high LDL-cholesterol (LDL-C) level and untreated vision loss – according to a report of the 2024 Lancet Commission on dementia.