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Video game-based intervention improves attention, cognition in major depression
An investigational digital intervention delivered through a video game–based interface, called AKL-T03, significantly improves attention span and cognitive functioning among patients with major depression when compared to a control condition, a study has shown. In addition, it is well tolerated and has minimal adverse events.

Meta-analysis favours citalopram in poststroke recovery
Selective serotonin reuptake inhibitors (SSRIs) can prevent and treat depression following stroke, in addition to improving anxiety, dependence, motor function, and cognitive function—benefits that are only reproducible with citalopram but not fluoxetine, according to a meta-analysis said to be the most up to date.

Dextromethorphan-bupropion relieves symptoms in major depressive disorder
Treatment with dextromethorphan-bupropion (AXS-05) significantly improves depressive symptoms relative to bupropion alone and is well tolerated in patients with major depression, results of a phase II trial have shown.

Ventral striatum connectivity may predict depression in adolescence
The connectivity strength of the ventral striatum (VS) within the reward network demonstrates links to depressive disorders and anhedonia from mid to late adolescence, which indicates the role played by this circuitry in depression changes with age, reveals a study.




