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Lecanemab moderately slows decline in early AD, associated with AEs

Lecanemab moderately slows decline in early AD, associated with AEs

06 Dec 2022 bởiNatalia Reoutova

Lecanemab reduces brain amyloid burden and offers moderate slowing of cognitive decline in early Alzheimer’s disease (AD), but is associated with adverse events (AEs), according to the results of the phase III, double-blind, placebo-controlled CLARITY AD trial, presented at the 15th Clinical Trials on Alzheimer’s Disease (CTAD 2022) conference.

06 Dec 2022
Dose reduction needed in HFrEF patients on sacubitril-valsartan

Dose reduction needed in HFrEF patients on sacubitril-valsartan

05 Dec 2022

Some patients with heart failure with reduced ejection fraction (HFrEF) need a loop diuretic dose reduction within 2‒3 months following initiation of sacubitril-valsartan, suggests a study.

05 Dec 2022
Dip in serum cholesterol tied to higher pancreatic cancer risk

Dip in serum cholesterol tied to higher pancreatic cancer risk

05 Dec 2022 bởiTristan Manalac

A recent decrease in total cholesterol levels may signal an aggravated risk of pancreatic cancer, reports a study. On the other hand, high serum cholesterol in the preceding years may exert a protective effect against pancreatic cancer.

05 Dec 2022