Tin tức & Cập nhật

Individuals who eat high amounts of ultra-processed food and lower amounts of unprocessed or minimally processed food are at increased risk of Crohn’s disease (CD) but not ulcerative colitis (UC), as reported in a study.

A six-month intervention with supervised exercise and home-based physical activity was associated with reduced atrial fibrillation (AF) recurrence and symptom severity among patients with symptomatic AF, according to the ACTIVE-AF* trial.

The COVID-19 pandemic continues to evolve with the emergence of new SARS-CoV-2 variants. The variants of concern have the potential to impact the transmissibility, virulence, and clinical presentation of the disease, affecting the epidemiology, public health measures, and diagnostic and therapeutic options. Mutations in the spike protein of the virus have increased its ability to infect humans and evade neutralization by natural or immunisation-induced antibodies. The highly mutated Omicron variant of SARS-CoV-2 has multiple sublineages with varying transmissibility and immune evasion potential. Pre-exposure prophylaxis plays a crucial role in protecting the immunocompromised populations against severe disease; however, the rapidly changing landscape of the variants poses a major challenge to the current and future effectiveness of pre-exposure prophylactic monoclonal antibodies.

Treatment with the nonpurine xanthine oxidase inhibitor tigulixostat leads to a significant reduction in serum uric acid (sUA) levels while having an acceptable safety profile, as shown in data from the multicentre, double-blind, parallel-group, dose-finding phase II CLUE trial.

Alcohol consumption appears to influence outcomes in patients with rheumatoid arthritis (RA), with a recent study showing that low to moderate drinkers have a lower disease activity and higher health-related quality of life than abstainers.