Tin tức & Cập nhật

Adding pembrolizumab to chemotherapy significantly improved survival outcomes and response rate compared with chemo alone in patients with locally advanced or metastatic HER2-negative gastric or gastroesophageal junction (G/GEJ) adenocarcinoma, according to the updated results of the KEYNOTE-859 study presented at ESMO WCGIC 2023.

In a prospective study from China, a novel noninvasive stool DNA methylation assay showed promise for the early detection of multiple gastrointestinal (GI) cancers.

Trong một phân tích con của một thử nghiệm giai đoạn 2 về béo phì, retatrutide, một “triagonist” của GIP*,GLP** và thụ thể glucagon, cho thấy nhiều tín hiệu khả quan về bệnh gan nhiễm mỡ không do rượu (NAFLD).

Treatment with tremelimumab plus durvalumab (STRIDE* regimen) continues to yield overall survival (OS) benefit at 4 years among patients with unresectable hepatocellular carcinoma (uHCC) compared with sorafenib, according to the updated results of the HIMALAYA trial presented at ESMO WCGIC 2023.

Children and adults with atopic dermatitis (AD) are at risk of inflammatory bowel disease (IBD), with the risk varying by age, AD severity, and IBD subtype, according to a study.

Adjuvant radiotherapy following endoscopic submucosal dissection (ESD) results in better survival in patients with lymphovascular invasion (LVI) in T1bN0M0 esophageal squamous cell cancer (ESCC), a study has shown.

Endoscopic ultrasound (EUS)–guided choledocho-doudenostomy (ECDS) can be an option for primary biliary drainage in patients with unresectable malignant distal biliary obstruction (MDBO), and may be preferred when endoscopic retrograde cholangiopancreatography (ERCP) is anticipated to be difficult, according an international randomized controlled trial (RCT) led by researchers from the Chinese University of Hong Kong (CUHK).