Tin tức & Cập nhật

Cerebral perfusion studies (CPS) can enhance the benefits of mechanical thrombectomy (MT) beyond the standard 6-hour post-stroke window, although favourable functional outcomes remain achievable in a substantial proportion of patients selected based on clinical judgement alone without CPS. These findings, from a study by researchers at the University of Hong Kong (HKU), suggest that stroke patients should not be routinely denied treatment solely because of delayed presentation or lack of CPS availability.

The oral dihydropyridine calcium channel blocker (CCB) amlodipine appears more beneficial than the beta-blocker metoprolol for managing hypertension in patients with heart failure with preserved ejection fraction (HFpEF), with greater effects on blood pressure (BP) control and exercise capacity, as shown in a randomized crossover trial.

Social determinants of health (SDOH) are significantly associated with maxillofacial trauma, suggests a US study. These SDOH factors include substance use, unhoused status, and poverty, among others

In the phase III RISE UP trial, mitapivat—approved for pyruvate kinase (PK) deficiency and thalassemia—shows a strong antihaemolytic effect in individuals with sickle cell disease (SCD).

Patients with asthma and chronic obstructive pulmonary disease (COPD) appear to have an elevated risk of pertussis infection, according to the results of a systematic review and meta-analysis.

For children and young adults with acute myeloid leukaemia (AML) and measurable residual disease (MRD) negativity, proceeding to allogeneic hematopoietic stem cell transplant (HSCT) after two rounds of chemotherapy is as effective as completing a third cycle prior to HSCT, yielding similar transplant outcomes, according to a multicentre retrospective study.

Long-term treatment with intravitreal antivascular endothelial growth factor (anti-VEGF) appears to elevate the risk of developing cataract that requires surgical intervention, reports a study.