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Potential therapeutic targets and repurposed drug identified for endometriosis
Researchers from the Chinese University of Hong Kong (CUHK) have identified two novel potential therapeutic targets and a drug approved for dry eyes that can be repurposed for treatment of endometriosis.
Potential therapeutic targets and repurposed drug identified for endometriosis
23 Jan 2025
Risk-reducing surgeries tied to improved outcomes in BRCA carriers with young-onset BC
A large global study provides evidence that risk-reducing mastectomy (RRM) and/or risk-reducing salpingo-oophorectomy (RRSO) is associated with improved survival outcomes in young women diagnosed with breast cancer (BC) at or before 40 years of age who were harbouring germline BRCA1 and/or BRCA2 pathogenic variants (PVs).
Risk-reducing surgeries tied to improved outcomes in BRCA carriers with young-onset BC
20 Jan 2025
Add-on palbociclib may overcome resistance to anti-HER2 Tx, ET in HR+, HER2+ mBC
The addition of the CDK4/6 inhibitor palbociclib to anti-HER2 and endocrine therapy (ET) significantly improves progression-free survival (PFS) in patients with hormone receptor-positive, HER-positive (HR+, HER+) metastatic breast cancer (mBC) in the first-line setting, according to the results of the phase III AFT-38 PATINA trial.
