Tin tức & Cập nhật

In patients with first-episode psychosis who did not respond to initial antipsychotic treatment, the use of clozapine appears to improve clinical outcomes better than olanzapine and amisulpride, according to a study.

Deprescribing among older adults can be improved by overcoming systemic barriers, enhancing patient education, and implementing structured guidelines, suggests a study.

Thulium fibre laser enucleation of the prostate (ThuFLEP) was noninferior to Holmium laser enucleation of the prostate (HoLEP) regarding functional outcomes over 24 months in patients with benign prostatic obstruction (BPO), according to a trial presented at EAU26.

Treatment with enzalutamide monotherapy demonstrates numerically higher overall survival (OS) in prostate cancer patients with high-risk biochemical recurrence (hrBCR) when compared with leuprolide alone, but the difference is not statistically significant, as shown by the results of the EMBARK study.

Treatment with upadacitinib induces clinical remission and endoscopic improvement in most patients with severe, refractory Crohn’s disease (CD) or ulcerative colitis (UC) with prior tofacitinib failure, regardless of previous response to tofacitinib, a study has shown.

The POISE-3 trial supports the use of tranexamic acid (TXA) in patients undergoing urologic surgery at increased risk of bleeding.

Acid suppressants such as potassium-competitive acid blockers (P-CABs) and proton pump inhibitors (PPIs), when used concomitantly with clopidogrel, carry an increased risk of ischaemic events in stroke patients, according to a retrospective cohort study.

In children with acute nonoperative musculoskeletal injury, treatment with ibuprofen alone appears adequate for relieving pain, with the addition of acetaminophen or hydromorphone yielding no additional analgesic effect, as shown in two No OUCH randomized clinical trials.

Poisoned individuals form a substantial part of the patient population in Singapore, with prognoses that require early recognition and appropriate measures, according to a study.