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Dolutegravir plus lamivudine suppresses HIV without HBV reactivation
The two-drug regimen dolutegravir plus lamivudine (DTG/3TC) is as good as 3- or 4-drug antiretroviral therapy (ART) regimens at keeping viral load suppressed while helping avoid hepatitis B virus (HBV) reactivation in people living with HIV-1 who have past exposure to HBV but no immunity, according to a post hoc analysis of five phase 3/3b studies.

PT-led on par with rheumatologist triage of joint pain referrals
A triage led by a physiotherapist (PT) performs as reliably as a rheumatologist triage of referrals for joint pain, with significantly fewer patients with inflammatory arthritis (IA) needing an in-clinic visit, a recent study has shown.

Gut microbiota may unlock new diagnostic and treatment strategies for autism
Gut microbiota biomarkers show >90 percent sensitivity and specificity in diagnosing autism spectrum disorder (ASD). Gut microbiome modulation with a novel synbiotic formula, SCM06, may alleviate anxiety symptoms in children with ASD, according to researchers from the Chinese University of Hong Kong (CUHK).

Biosimilar DMARDs cost-effective vs leflunomide in RA patients after MTX failure
An economic evaluation study by the University of Hong Kong (HKU) found treatment with biosimilar disease-modifying antirheumatic drugs (DMARDs) to be cost-effective compared with leflunomide in patients with rheumatoid arthritis (RA) who failed initial treatment with methotrexate (MTX).





