Tin tức & Cập nhật

New drug applications approved by US FDA as of 16 - 31 July 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Adding pembrolizumab to chemotherapy in the first-line setting significantly prolongs overall survival (OS) in patients with triple-negative breast cancer (TNBC) whose tumours expressed programmed death-ligand 1 (PD-L1) with a CPS* of ≥10, compared with chemotherapy alone, according to the KEYNOTE-355** trial.

Polypharmacy frequently occurs in most patients with advanced cancer at end of life, reports a recent study. However, most medications used are usually for supportive care.

Use of the calcium channel blocker verapamil is both safe and effective for the treatment of Peyronie’s disease, as proven by a decrease in penile curvature, reduction in plaque size, and improvement in erectile dysfunction, with minimal to mild side effects, relative to placebo, according to the results of a systematic review and meta-analysis.

In the maintenance treatment of patients with lupus nephritis (LN), leflunomide is as effective and safe as azathioprine, according to a study.