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Baricitinib BREEZEs through in atopic dermatitis

25 May 2021 bởi

In adults with moderate-to-severe atopic dermatitis (AD), use of the oral, selective Janus kinase 1/2 inhibitor baricitinib* led to significant improvements in quality of life (QoL) parameters in AD, accordingly to subgroup analyses results of the BREEZE-AD5 trial.

Baricitinib BREEZEs through in atopic dermatitis

25 May 2021

Inactive pills may lower reliance on opioids

25 May 2021

Open-label placebos (OLPs), which are placebos described honestly as inactive pills, appear to be favourably regarded by patients for managing pain after surgery, according to a study. As such, OLPs can be considered as an adjunctive treatment to potentially lessen the need for prescription opioids.

Inactive pills may lower reliance on opioids

25 May 2021

In utero antiseizure med exposure may not affect early neurodevelopment in children

24 May 2021 bởi

Exposure to antiseizure medications during pregnancy does not appear to affect neurodevelopmental outcomes in offspring at age 3 years, according to results of the MONEAD* study presented at AAN 2021.

In utero antiseizure med exposure may not affect early neurodevelopment in children

24 May 2021

Cutaneous reactions caused by BRAF, MEK inhibitors alter oncologic therapy in children

24 May 2021

Children treated with BRAF and MEK inhibitors are prone to cutaneous reactions, many of which result in alterations or interruptions in oncologic therapy, reports a study.

Cutaneous reactions caused by BRAF, MEK inhibitors alter oncologic therapy in children

24 May 2021

Antibiotic regimens proven safe in premature infants with intra-abdominal infections

24 May 2021 bởi

Three antibiotic regimens have been found safe and tolerable in critically ill premature infants with complicated intra-abdominal infections (CIAIs), a study has shown. No differences are seen in mortality, adverse events (AEs), or serious AEs between any of the commonly used antimicrobial regimens.

Antibiotic regimens proven safe in premature infants with intra-abdominal infections

24 May 2021

Polypharmacy in RA tied to several comorbidities

24 May 2021

Polypharmacy occurs generally in patients with rheumatoid arthritis, with a prevalence of 67.9 percent, and has shown a relationship with a number of comorbidities, according to a study. The researchers stress the need for solutions in managing this problem.

Polypharmacy in RA tied to several comorbidities

24 May 2021

One-month DAPT sufficient after PCI?

24 May 2021 bởi

Two separate analyses presented at SCAI 2021 demonstrated that a 1-month dual antiplatelet therapy (DAPT) following percutaneous coronary intervention (PCI) with a drug-eluting stent (DES) appears to be safe and effective for PCI patients at high risk of bleeding (ie, those with advanced age, chronic NSAID use, bleeding history, anaemia, thrombocytopenia, etc), compared with a DAPT regimen between 6 and 12 months.

One-month DAPT sufficient after PCI?

24 May 2021

High- vs low-strength insulin glargine tied to fewer hypoglycaemic events

24 May 2021

Insulin glargine at 300 U/mL (Gla-300) affords similar glycaemic control as that at 100 U/mL (Gla-100) in East Asian patients, although the former is associated with consistently fewer hypoglycaemic events at any time of the day and night, according to the results of a meta-analysis.

High- vs low-strength insulin glargine tied to fewer hypoglycaemic events

24 May 2021

His-bundle pacing gains foothold in heart failure with LBBB

23 May 2021 bởi

Cardiac resynchronization therapy (CRT) with His-bundle pacing led to successful and lasting cardiac resynchronization in almost three-quarters of patients with symptomatic heart failure (HF) and left bundle branch block (LBBB), shows the His-Alternative study presented at EHRA 2021.

His-bundle pacing gains foothold in heart failure with LBBB

23 May 2021

Continuous diuretic use averts hyponatraemia hospitalization

23 May 2021

Patients with ongoing use of furosemide are at decreased risk of being hospitalized due to hyponatraemia, according to a study, suggesting that this type of diuretic may have a protective effect.

Continuous diuretic use averts hyponatraemia hospitalization

23 May 2021

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Baricitinib BREEZEs through in atopic dermatitis

Baricitinib BREEZEs through in atopic dermatitis

Inactive pills may lower reliance on opioids

Inactive pills may lower reliance on opioids

In utero antiseizure med exposure may not affect early neurodevelopment in children

In utero antiseizure med exposure may not affect early neurodevelopment in children

Cutaneous reactions caused by BRAF, MEK inhibitors alter oncologic therapy in children

Cutaneous reactions caused by BRAF, MEK inhibitors alter oncologic therapy in children

Antibiotic regimens proven safe in premature infants with intra-abdominal infections

Antibiotic regimens proven safe in premature infants with intra-abdominal infections

Polypharmacy in RA tied to several comorbidities

Polypharmacy in RA tied to several comorbidities

One-month DAPT sufficient after PCI?

One-month DAPT sufficient after PCI?

High- vs low-strength insulin glargine tied to fewer hypoglycaemic events

High- vs low-strength insulin glargine tied to fewer hypoglycaemic events

His-bundle pacing gains foothold in heart failure with LBBB

His-bundle pacing gains foothold in heart failure with LBBB

Continuous diuretic use averts hyponatraemia hospitalization

Continuous diuretic use averts hyponatraemia hospitalization