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Extension study reflects durable efficacy, safety of tildrakizumab for plaque psoriasis

27 May 2021 bởi

The high-affinity, humanized, anti-interleukin-23-p19 monoclonal antibody tildrakizumab showed durable efficacy and safety for the treatment of chronic plaque psoriasis, according to the week 256 findings of the reSURFACE 1 trial.

Extension study reflects durable efficacy, safety of tildrakizumab for plaque psoriasis

27 May 2021

Cyclophosphamide-free chemo may promote menses resumption

27 May 2021

Breast cancer patients receiving treatment with a cyclophosphamide-free chemotherapy regimen are likely to resume their menses, according to a phase III trial.

Cyclophosphamide-free chemo may promote menses resumption

27 May 2021

Personalized- better than fixed-dose steroid dosing for COPD exacerbations

27 May 2021

In the treatment of hospitalized chronic obstructive pulmonary disorder (COPD) patients with exacerbations, personalized-dose corticosteroid dosing is more effective than fixed-dose, as reported in a study.

Personalized- better than fixed-dose steroid dosing for COPD exacerbations

27 May 2021

COVID-19 vaccines prove their mettle against B.1.351 variant

26 May 2021 bởi

Available COVID-19 vaccines remain highly protective against currently circulating SARS-CoV-2 variants of concern — including the South Africa B.1.351 strain — despite initial concerns of dented antibody neutralization activity, suggests growing evidence from real world and randomized studies.

COVID-19 vaccines prove their mettle against B.1.351 variant

26 May 2021

Perinatal depression in women with HIV interferes with viral suppression

26 May 2021

Pregnant women who exhibit depressive symptoms are highly likely to have decreased adherence to antiretroviral therapy (ART), which negatively affects viral suppression, a study reports.

Perinatal depression in women with HIV interferes with viral suppression

26 May 2021

Fenofibrate delays need for dialysis, cuts CV risk in advanced CKD

26 May 2021

Use of fenofibrate provides cardiovascular (CV) benefits similar to that of statins and may even delay the need for permanent dialysis in patients with advanced chronic kidney disease (CKD), a study has shown. Moreover, the combination of fenofibrate and high-intensity statins may deliver additional benefits.

Fenofibrate delays need for dialysis, cuts CV risk in advanced CKD

26 May 2021

Cotadutide confers benefits for glucose control, weight loss in obese T2D patients

26 May 2021

Treatment with the dual GLP-1 and glucagon receptor agonist cotadutide leads to improved glycaemic control and weight loss in type 2 diabetes (T2D) patients who are overweight or obese, according to a phase IIb study.

Cotadutide confers benefits for glucose control, weight loss in obese T2D patients

26 May 2021

Bimekizumab tops adalimumab in moderate-to-severe plaque psoriasis

25 May 2021 bởi

Bimekizumab, a monoclonal IgG1 antibody that selectively inhibits interleukin-17A and interleukin-17F, was superior to adalimumab in reducing the severity of plaque psoriasis, according to results of a phase III trial presented at AAD 2021.

Bimekizumab tops adalimumab in moderate-to-severe plaque psoriasis

25 May 2021

Early remdesivir initiation optimal in moderate-to-severe COVID-19

25 May 2021 bởi

In patients with COVID-19, starting remdesivir within 9 days of symptom onset confers benefit for survival, according to a study.

Early remdesivir initiation optimal in moderate-to-severe COVID-19

25 May 2021

Ceftobiprole on par with cephalosporin for treatment of paediatric pneumonia

25 May 2021 bởi

A small phase III trial has found that ceftobiprole is well tolerated and as efficacious as standard-of-care (SoC) cephalosporins in paediatric patients with hospital- (HAP) or community-acquired pneumonia (CAP) requiring hospitalization.

Ceftobiprole on par with cephalosporin for treatment of paediatric pneumonia

25 May 2021

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Extension study reflects durable efficacy, safety of tildrakizumab for plaque psoriasis

Extension study reflects durable efficacy, safety of tildrakizumab for plaque psoriasis

Cyclophosphamide-free chemo may promote menses resumption

Cyclophosphamide-free chemo may promote menses resumption

Personalized- better than fixed-dose steroid dosing for COPD exacerbations

Personalized- better than fixed-dose steroid dosing for COPD exacerbations

COVID-19 vaccines prove their mettle against B.1.351 variant

COVID-19 vaccines prove their mettle against B.1.351 variant

Perinatal depression in women with HIV interferes with viral suppression

Perinatal depression in women with HIV interferes with viral suppression

Fenofibrate delays need for dialysis, cuts CV risk in advanced CKD

Fenofibrate delays need for dialysis, cuts CV risk in advanced CKD

Cotadutide confers benefits for glucose control, weight loss in obese T2D patients

Cotadutide confers benefits for glucose control, weight loss in obese T2D patients

Bimekizumab tops adalimumab in moderate-to-severe plaque psoriasis

Bimekizumab tops adalimumab in moderate-to-severe plaque psoriasis

Early remdesivir initiation optimal in moderate-to-severe COVID-19

Early remdesivir initiation optimal in moderate-to-severe COVID-19

Ceftobiprole on par with cephalosporin for treatment of paediatric pneumonia

Ceftobiprole on par with cephalosporin for treatment of paediatric pneumonia