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Lower phase angle linked to CKD progression in T2DM
A Singapore study has found a previously overlooked connection between bioelectrical impedance analysis (BIA)-derived lower phase angle and chronic kidney disease (CKD) progression, mediated by matrix metalloproteinase-2 (MMP-2), in patients with type 2 diabetes mellitus (T2DM).

Immune-related AEs tied to improved survival in bladder cancer patients on atezolizumab
In patients with locally advanced or metastatic urothelial cancer patients receiving atezolizumab treatment, immune-related adverse events (AEs) were associated with improved survival outcomes, according to an analysis of individual participant data from the IMvigor210 and IMvigor211 studies.

EAGLE trials herald new era for uncomplicated UTI treatment
Oral gepotidacin, an investigational, first-in-class oral antibiotic with a novel mechanism of action, showed favourable signals for the treatment of uncomplicated urinary tract infections (uUTIs), according to the results of two phase III trials.





