Tin tức & Cập nhật

Factors such as APOE4 allele, dementia onset before age 60 years, Alzheimer’s disease (AD) dementia subtype, worse cognition, stroke/transient ischaemic attack (TIA), and Parkinson’s disease (PD) all contribute to a heightened risk of late-onset epilepsy in people with cognitive decline, as reported in a study.

Fremanezumab appears to provide a two-for-one benefit in patients with migraine and comorbid depressive disorder, with data from the UNITE study showing that the drug helped reduce migraine days and lift mood.

Among women with a history of pregnancy loss, prior exposure to Chlamydia trachomatis poses an increased risk of miscarriage, as reported in a study.

Treatment with targeted-release budesonide formulation preserves kidney function and reduces proteinuria in patients with IgA nephropathy (IgAN) independent of baseline eGFR, and this benefit is seen both after 9 months of treatment and throughout the remaining 15-month off-treatment period, according to a subanalysis of the phase III NeflgArd study presented at the ERA annual meeting.

Supplementation with probiotics appears to induce an acute effect on reaction times during executive function, hinting at the possibility of preventing the development of depression among older adults, according to a study.

Treatment with steady-state, low-dose morphine does not appear to improve sleep efficiency, sleep-disordered breathing frequency, or next-day alertness but may rather result in hypoventilation during sleep in chronic obstructive pulmonary disease (COPD) patients with chronic breathlessness, according to the results of a randomized, double-anonymized, crossover trial.

Maintenance treatment with vedolizumab proved safe and effective in paediatric inflammatory bowel disease (IBD), with long-term remission achieved more frequently in children with ulcerative colitis (UC) than in those with Crohn’s disease (CD), according to the final 3-year data from the VEDOKIDS study.

A lifestyle pattern with higher insulinemic potential may predispose an individual to endometrial cancer (EC), suggests a study.