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Opioid use lowers LOS, deaths in nonmetastatic CRC patients
Use of opioids in the long term leads to shorter length of stay (LOS) and reduced inpatient mortality among patients hospitalized with nonmetastatic colorectal cancer (CRC), results of a study have shown. However, patients with cancer-related complications endure longer LOS and higher mortality than those admitted without such morbidities.
Shorter time from rectal cancer diagnosis to NCRT tied to pathologic complete response
The time elapsed between diagnosis of rectal cancer and initiation of neoadjuvant chemoradiation (NCRT) shows a significant association with pathologic complete response (pCR), and shortening this time may improve the likelihood of achieving pCR, suggests a recent study.
Belzutifan a ray of hope for VHL-associated renal cancer?
In a phase II study, the novel oral HIF*-2α inhibitor belzutifan showed promise for individuals with renal cell carcinoma (RCC) associated with von Hippel-Lindau (VHL) disease, a rare autosomal dominant hereditary disease associated with benign and malignant neoplasms, including clear-cell RCC, pancreatic neuroendocrine tumours, and CNS** and retinal hemangioblastomas.
First-line cabozantinib-atezolizumab boosts PFS in advanced HCC
The combination of cabozantinib and atezolizumab in the first-line setting significantly improved progression-free survival (PFS) compared with sorafenib in patients with advanced hepatocellular carcinoma (HCC), according to results of the phase III COSMIC-312 trial presented at ESMO Asia 2021.