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Overeating a marker of poor mental health, adverse outcomes among teens with diabetes
Overeating or binge eating symptoms are linked to lower quality of life, higher prevalence of depression and anxiety, and poor clinical outcomes among adolescents with type 1 diabetes, according to a study.

Cardiorenal benefit with investigational GLP-1 RA independent of concurrent SGLT2 inhibitor
The glucagon-like peptide-1 receptor agonist (GLP-1 RA) efpeglenatide affords cardiovascular and renal protection that is not explained by concurrent use of a sodium-glucose co-transporter-2 (SGLT2) inhibitor in patients with type 2 diabetes (T2D), according to an exploratory analysis of AMPLITUDE-O.

Remnant cholesterol tied to CVD death in patients with T2D, CKD, diabetic nephropathy
Remnant cholesterol (C) appears predictive of mortality due to cardiovascular disease (CVD) among patients with type 2 diabetes (T2D), chronic kidney disease (CKD) stage 3 to 5, and incident diabetic nephropathy (DN), suggests a study.

Insulin secretion predicts response to therapy in new-onset diabetes
The increase in C-peptide (C-Pep) above fasting following glucose load is associated with response to antihyperglycaemic therapy in patients with new-onset type 2 diabetes mellitus (T2DM), according to a study. The plasma C-Pep concentration ratio (C-Pep120/C-Pep0) may be used for the individualization of such therapy in this population.

Homocysteine tied to spinal osteoarthritis prevalence in postmenopausal women
Circulating homocysteine and C677T variant in methylenetetrahydrofolate reductase (MTHFR) appear to influence the prevalence rate and ensuing progression of spinal osteoarthritis (OA), respectively, in postmenopausal women, a study has shown.



