Tin tức & Cập nhật

Pregnant women with high levels of thyroid stimulating hormone (TSH), which indicate hypothyroidism, are at risk of adverse pregnancy outcomes, a study has found.

In a cohort of middle-aged individuals from South Korea, the initial weight loss at 4 years appears to contribute to an increased risk of major adverse cardiovascular events (MACEs), which may be explained by residual cardiovascular burden, according to a study. However, the risk increase disappears among individuals with sustained weight loss ≥ 6 years.

Women with very high levels of high-density lipoprotein cholesterol (HDL-C) are at heightened risk of cardiovascular mortality, with the association following a J-shaped pattern, as reported in a study. Of note, the risk of cardiovascular mortality increases with concomitant hyperuricaemia.

PCSK9 inhibitors alirocumab and evolocumab are not only safe and well tolerated but also efficacious in Asian patients, results of a real-world study in Singapore have shown. However, about a third of patients stopped using these medications due to their high costs.