Tin tức & Cập nhật

Respiratory syncytial virus (RSV) remains a leading cause of hospitalisation and severe lower respiratory tract infection (LRTI) in infants worldwide. [Lancet 2022;399:2047-2064; Lancet 2017;390:946-958] In recent years, two immunoprophylactic strategies have become available to protect infants, namely maternal immunisation with the RSV prefusion F (RSVpreF) vaccine and passive immunisation of infants with the long-acting monoclonal antibody nirsevimab.

For hospitalized cancer patients, contracting Clostridioides difficile infection (CDI) contributes to a substantial increase in mortality and healthcare resource use, according to a cross-sectional study.

Adults with obesity are at increased risk of infection-related hospitalizations and mortality, with a 10th of infection-related deaths estimated to be attributable to obesity, according to a study.

Gastroesophageal reflux disease (GERD) and its complications appear to increase the risk of nontuberculous mycobacterium (NTM) infection, suggests a study.

The investigational combination of doravirine plus islatravir (DOR/ISL)—a fixed-dose, once-daily oral antiretroviral therapy (ART) regimen that does not rely on integrase strand-transfer inhibitors (INSTIs)—is shaping up to be a promising alternative in the management of HIV, showing noninferiority to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) in individuals initiating treatment for the first time and maintaining virologic suppression in those switching from various ART regimens, as shown in three phase III studies presented at CROI 2026.