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Use of 5αRI does not increase cardiovascular risk in men with BPH
Treatment with five-alpha reductase inhibitors (5αRIs) does not appear to elevate the risk of hospitalization for heart failure (HF), myocardial infarction (MI), stroke, or cardiovascular death among men with benign prostatic hyperplasia (BPH), a study has shown.
Lorundrostat may expand treatment toolbox for uncontrolled hypertension
Aldosterone synthase inhibition with lorundrostat confers substantial blood pressure (BP)-lowering benefit in people with uncontrolled hypertension, while having a favourable safety profile, according to data from the phase II Target-HTN trial.
Treating hypertension helps lower dementia risk in older adults
Older adults with hypertension who are on blood pressure (BP)-lowering medications are better protected against dementia than those with untreated hypertension, and this is true across all ages in late life, according to an individual participant data meta-analysis.
