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Catheter-based ultrasound renal denervation produces similar blood pressure (BP)-lowering effects as sham procedure in Asian patients with resistant hypertension receiving antihypertensive therapy, according to the results of the REQUIRE trial.

The mouth a gateway to stroke risk reduction?

16 Feb 2022 bởi

In individuals who had a recent stroke or transient ischaemic attack (TIA), a trip to the dentist might just spare them from a recurrence, findings from the PREMIERS* study suggest.

16 Feb 2022

Original New Drug Application Approvals by US FDA (01 - 15 February 2022)

New drug applications approved by US FDA as of 01-15 February 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

COVID-19 infection relatively rare in vaccinated IBD patients

Patients with inflammatory bowel disease (IBD) who have completed a COVID-19 vaccine regimen have a low risk of developing COVID-19, though receipt of mRNA vaccines may offer better protection, according to a small study presented at the Crohn’s and Colitis Congress 2022.

15 Feb 2022

ATRA-ATO combo safe, effective in acute promyelocytic leukaemia

Real-world data confirm that the combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) is an effective treatment regimen for patients with acute promyelocytic leukaemia (APL), a recent study suggests.

A next-generation COVID-19 vaccine will be puffed in the nose

Getting inoculated against COVID-19 with a jab into the upper arm has proven to be reliable, but the appearance of new, troublesome SARS-COV-2 variants continues to threaten the efficacy of existing vaccines. A better strategy, some say, is a multivalent vaccine delivered directly into the respiratory tract by inhalation, as it can provide broader protection and greater durability.

High BMI, lipoprotein(a) levels up risk of calcific aortic valve disease

The combination of extremely high lipoprotein(a) levels and body mass index (BMI) results in a 3.5-fold increased risk of calcific aortic valve disease (CAVD), according to a recent study. The 10-year absolute risk of CAVD by categories of lipoprotein(a) levels, BMI, age, and sex ranges from 0.4 percent to 14 percent.

Microneedle technology on par with topical steroids in nail psoriasis treatment

A novel transdermal device for the delivery of triamcinolone demonstrates efficacy comparable to that of conventional topical steroids in the treatment of nail psoriasis, according to a Singapore study.

15 Feb 2022

Stroke may occur before/after central retinal artery occlusion

A 2.2-percent risk of symptomatic ischaemic stroke has been observed 15 days before and after a central retinal artery occlusion (CRAO), suggests a recent study, noting that such risk is slightly lower than that for most studies from tertiary centres.

15 Feb 2022

Otolith dysfunction common among patients with dizziness

Among patients who present to the hospital with dizziness, the prevalence of isolated otolith dysfunction (iOD) is high, according to a recent Singapore study, which emphasizes the need for a more routine performance of laboratory tests of otolith function.