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Booster COVID-19 vacc cuts breakthrough infection risk, particularly in individuals with no immune dysfunction
Receipt of a booster dose of the COVID-19 vaccine reduces the risk of breakthrough COVID-19 infections* compared to full vaccination only, particularly among individuals without immunosuppressed/compromised conditions (ISC), according to a US study presented at CROI 2022.

Investigational DP2 antagonist strikes out in eosinophilic asthma
The prostaglandin D2 receptor 2 (DP2) antagonist GB001 does not appear to significantly lower the risk of disease worsening in patients with moderate-to-severe eosinophilic asthma, according to data from a phase IIb trial.

Shorter antibiotic regimen enough in kids with pneumonia?
Children with non-severe community-acquired pneumonia (CAP) may benefit from a 5-day antibiotic regimen compared with the current standard regimen of 10 days, according to results of the US-based SCOUT-CAP trial.

Delamanid-based regimens work against multidrug-resistant tuberculosis
The use of delamanid-containing regimens is safe and effective in the management of multidrug-resistant tuberculosis (MDR-TB), with high culture conversion and treatment success rates despite extensive resistance patterns, according to the results of a meta-analysis.

Female sex, hypertension, number of initial symptoms tied to long COVID risk
The risk of developing long COVID is high among women, hypertensives, and those with a higher number of initial symptoms, and these associations are independent of disease severity and clinical course, a study has found.

Post-COVID sequelae conditions identified, could help establish definition
Patients diagnosed with COVID-19 could have an increased risk of certain conditions up to 120 days post-diagnosis, a finding which could help establish the definition of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), according to a study presented at CROI 2022.


