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β3 agonist safe, effective for treatment of bladder dysfunction in children
ß3-adrenergic receptor agonists (ß3 agonists), such as mirabegron, demonstrate effectiveness and a satisfactory safety profile as adjunctive therapy in the management of paediatric neurogenic detrusor overactivity (NDO) or overactive bladder, results of a study have shown.

Corticosteroids help prevent hearing loss, neurologic sequelae in paediatric bacterial meningitis
Children with bacterial meningitis appear to fare well with corticosteroids, which lead to a lower incidence of hearing loss and neurologic sequelae and faster resolution of fever, according to a meta-analysis.

Sofosbuvir easy on the kidneys
Use of sofosbuvir-based direct-acting antiviral regimens for treating hepatitis C virus (HCV) in clinical trial participants with chronic kidney disease (CKD) does not appear to worsen estimated glomerular filtration rate levels, according to a study. Furthermore, the drug does not appear to contribute to an increased risk of end-stage renal disease among HCV patients with CKD treated in clinical practice.






