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Acute kidney, liver injury risks with remdesivir pinned to underlying SARS-CoV-2 infection
Treatment with remdesivir in patients hospitalized for COVID-19 does not appear to confer increased risks of acute kidney and liver injury, with a recent study showing that these risks are already elevated even before exposure to treatment and there is no further increase following remdesivir initiation.
Group CBT with interoceptive exposure safe, effective for drug-refractory IBS
Group cognitive behavioural therapy (GCBT) with interoceptive exposure (IE) is not only safe and effective but also an efficient treatment option for individuals with drug-refractory irritable bowel syndrome (IBS), according to a Japan study.
CYP39A1 G204E variant ups risk of glaucoma, blindness in patients with exfoliation syndrome
Patients with exfoliating syndrome (XFS) who carry the CYP39A1 G204E mutation are at significantly higher risk of blindness, have higher occurrence of exfoliation glaucoma (XFG), and display more severe glaucoma than those with XFS without any CYP39A1 mutation, reveals a study.
Early molnupiravir use benefits unvaccinated COVID-19 outpatients
Early administration (ie, within 5 days after symptom onset) of the oral, small-molecule antiviral prodrug molnupiravir slashed the risk of hospitalization or death in at-risk, unvaccinated, nonhospitalized adults with mild-to-moderate COVID-19, findings from the phase III component of the phase II/III MOVe-OUT trial have shown.
