|
Chỉ định và Liều dùng
Ophthalmic
Ocular infections Adult: As 10%, 15% or 30% sulfacetamide Na soln: Instill 1-2 drops into the conjunctival sac of the affected eyes(s) 2-3 hourly. As 10% sulfacetamide Na ointment: Apply approx half inch onto affected eye(s) 3-4 hourly and at bedtime. Taper dose by increasing dosage time interval as condition responds. Usual duration of treatment: 7-10 days.
|
|
Các sản phẩm có chứa hoạt chất Sulfacetamide tại Việt Nam?
|
|
Chống chỉ định
Hypersensitivity; infants <2 mth.
|
|
Thận trọng
Elderly. History of allergy or asthma; G6PD deficiency; renal and hepatic impairment. Prolonged therapy requires CBC and urinalysis with microscopic examination. Maintain adequate fluid intake. Pregnancy, lactation.
|
|
Tác dụng không mong muốn
Hypersensitivity skin reaction. Ophthalmic: Burning, stinging, conjunctivitis, corneal ulcers, irritation, conjunctival hyperaemia. Systemic absorption from inflamed conjunctiva.
Potentially Fatal: Stevens-Johnson syndrome. |
|
Ophth/Topical: C
|
|
Tương tác
Action antagonised by PABA and procaine group of local anaesthetics. PABA present in purulent eye exudates can competitively inhibit the action of sulphacetamide.
|
|
Ảnh hưởng đến kết quả xét nghiệm
May interfere with diagnostic tests e.g. urinary glucose, urobilinogen, urea and creatinine.
|
|
Tác dụng
Description:
Mechanism of Action: Sulfacetamide has bacteriostatic effect on a wide range of gram-positive and gram-negative organisms. It interferes with nucleic acid synthesis thus blocking conversion of PABA to the coenzyme dihydrofolic acid. Pharmacokinetics: Absorption: Penetrates into ocular tissues and fluids (ophthalmic). Excretion: Urine (as unchanged drug); 7-13 hr (elimination half-life). |
|
Bảo quản
Store below 25°C.
|
|
Phân loại MIMS
|
Đăng ký miễn phí để được tiếp tục đọc
Tiếp tục với Google
Đăng ký với email
Đã là thành viên?
Đăng nhập
Đăng xuất
