Adult: As 0.5% susp: Instill 1-2 drops onto affected eye(s) 4 times daily, beginning 24 hr after surgery and continuing through the 1st 14 days of post-op period. As 0.5% oint: Apply approx 1/2 inch ribbon into the conjunctival sac onto the affected eye(s) 4 times daily, beginning 24 hr after surgery and continuing through the 1st 14 days of post-op period. As 0.5% gel: Instill 1-2 drops to the affected eye(s) 4 times daily, beginning 24 hr after surgery and continuing through the 1st 14 days of post-op period.
Ophthalmic Seasonal allergic conjunctivitis
Adult: As 0.2% susp: Instill 1 drop onto affected eye(s) 4 times daily.
Ophthalmic Allergic and inflammatory conditions of the eye
Adult: As 0.5% susp: Instill 1-2 drops onto affected eye(s) 4 times daily.
Các sản phẩm có chứa hoạt chất Loteprednol tại Việt Nam?
Remove contact lenses prior to ophth admin and reinsert after 15 min. This drug may cause transient effects on vision, if affected, do not drive or operate machinery.
Chỉ số theo dõi
Monitor intraocular pressure (if used for >10 days); signs and symptoms of other infections (e.g. fungal).
Tương tác
May increase the risk of intraocular pressure w/ cycloplegics and other ocular hypotensive agents.
Tác dụng
Description: Mechanism of Action: Loteprednol is a corticosteroid w/ a glucocorticoid activity. It is highly lipid soluble which enhances cell penetration to induce the production of lipocortin protein that modulates the activity of prostaglandin and leukotrienes resulting in the inhibition of inflammatory response. Onset: W/in 2 hr. Pharmacokinetics: Metabolism: Undergoes extensive metabolism into inactive carboxylic acid metabolite.
Đặc tính
Loteprednol Source: National Center for Biotechnology Information. PubChem Database. Loteprednol, CID=9865442, https://pubchem.ncbi.nlm.nih.gov/compound/Loteprednol (accessed on Jan. 22, 2020)
S01BA14 - loteprednol ; Belongs to the class of corticosteroids. Used in the treatment of inflammation of the eye.
Tài liệu tham khảo
Alrex Suspension Drops (Bausch & Lomd Incorporated). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 06/07/2017.Anon. Loteprednol Etabonate. AHFS Clinical Drug Information [online]. Bethesda, MD. American Society of Health-System Pharmacists, Inc. https://www.ahfscdi.com. Accessed 06/07/2017.Anon. Loteprednol. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 06/07/2017.Buckingham R (ed). Loteprednol Etabonate. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 06/07/2017.Joint Formulary Committee. Loteprednol Etabonate. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 06/07/2017.Lotemax Gel (Bausch & Lomd Incorporated). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 06/07/2017.Lotemax Ointment (Bausch & Lomd Incorporated). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 06/07/2017.Lotemax Suspension/Drops (Bausch & Lomd Incorporated). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 06/07/2017.