Acute migraine attacks
Adult: As mucate: 130 mg at the onset of an attack, then 65 mg hrly thereafter as necessary. Max dose: 325 mg in 12 hr.
|
Chỉ định và Liều dùng
Oral
Acute migraine attacks Adult: As mucate: 130 mg at the onset of an attack, then 65 mg hrly thereafter as necessary. Max dose: 325 mg in 12 hr.
|
|
Chống chỉ định
Porphyria; severe hypertension; severe renal and hepatic impairment; organic heart disease.
|
|
Thận trọng
CV diseases; hyperthyroidism; DM; pregnancy, lactation; angle-closure glaucoma.
|
|
Tác dụng không mong muốn
Dizziness, circulatory disturbances, rash, haematological disorders.
|
|
Tương tác
May antagonise hypotensive effects of adrenergic neurone blockers. Increased risk of hypertension with doxapram, oxytocin. Increased risk of ergotism with ergotamine and methysergide.
Potentially Fatal: Increased risk of hypertensive crisis with MAOIs, moclobemide. Increased risk of toxicity (severe hypertension) with bromocriptine. |
|
Tác dụng
Description:
Mechanism of Action: Isometheptene is an indirect-acting sympathomimetic and acts as a vasoconstrictor. |
|
Bảo quản
Store at controlled room temperature 15-30°C (59-86°F).
|
|
Phân loại MIMS
|