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Autoantibodies against type 1 interferons increase COVID-19 death risk
The presence of autoantibodies neutralizing type 1 interferons (IFN), such as IFN-α2 or IFN-ω, strongly increase the relative risk of death (RRD) and infection fatality rate (IFR) in unvaccinated patients with COVID-19, according to a recent study.

Treatment outcomes for nAMD, DMO, RVO poorer in clinical practice than in trials
In clinical practice, patients with neovascular age-related macular degeneration (nAMD), diabetic macular oedema (DMO), and retinal vein occlusion (RVO) see treatment outcomes that are inferior to those reported in pivotal phase 3 studies, according to a recent study.

CREATE: ‘Open-source’ automated insulin delivery gets good results in T1D
Automating insulin delivery with an open-source algorithm that is run on a smartphone proves safe and effective in the management of type 1 diabetes (T1D), as shown in the results of Community Derived Automated Insulin Delivery (CREATE) trial.





