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Diabetes, insulin use up risk of death, cardiac events in AF patients
In patients with atrial fibrillation (AF), being diabetic contributes to an increased risk of all-cause death, cardiovascular disease (CVD), myocardial infarction (MI), major bleeding, and major adverse cardiovascular events (MACE), results of the GLORIA-AF study have shown.
Fewer CV events after COVID-19 vaccine-related myocarditis
In a nationwide French cohort study, myocarditis attributed to COVID-19 mRNA vaccination causes fewer cardiovascular (CV) events at 18 months of follow-up than that attributed to SARS-CoV-2 infection or myocarditis of conventional aetiologies.
Tenecteplase at 4.5–24 hours without thrombectomy feasible for ischaemic stroke
The use of tenecteplase in the extended time window of 4.5–24 hours improves functional outcomes in patients with ischaemic stroke when endovascular thrombectomy (EVT) is not immediately available, findings from the phase III TRACE-III* trial suggest.
Four-drug pill beats three separate meds in difficult-to-treat hypertension
For individuals with difficult-to-treat hypertension who are struggling with three separate medications, a single pill that combines four blood pressure (BP)-lowering drugs may help with BP control, as shown in the phase III QUADRO trial.