News & Updates

Patients with brain metastasis from gynaecologic cancers often present with an advanced stage disease and have had at least one prior recurrence, according to a study. In addition, the presence of an extracranial disease is common at the time of brain metastasis diagnosis.

A randomized controlled trial of 190 patients from university teaching hospitals in Hong Kong, mainland China, and Australia finds that initial treatment of nonvariceal upper gastrointestinal (GI) bleeding with over-the-scope clips (OTSCs) reduces the risk of further bleeding vs standard endoscopic haemostatic treatment.

Adding dostarlimab, an immune checkpoint inhibitor, to standard-of-care chemotherapy significantly improves progression-free survival (PFS) in patients with primary advanced or recurrent endometrial cancer, including those with dMMR-MSI-H* disease, according to the first interim analysis of the ENGOT-EN6-NSGO/GOG-3031/RUBY trial presented at SGO 2023.

In the treatment of patients with familial hypercholesterolemia, adding alirocumab to high-intensity statin therapy leads to a significant reduction in plaque burden and plaque stabilization, according to data from the ARCHITECT* study.

Maximal endoscopic ablation prior to treatment with reverse thermal polymer gel of mitomycin C (UGN-101) treatment appears to lead to fewer patients with upper tract urothelial carcinoma at first endoscopy and fewer adverse events (AEs) when compared with primary chemoablative therapy, suggests a recent study.