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Chloride-potassium assessment helps diagnose thiazide-associated hyponatraemia
Assessment of apparent strong ion difference (aSID), potassium, and chloride in urine is a useful tool for classifying patients with volume-depleted thiazide-associated hyponatraemia (TAH) requiring fluid substitution relative to those with syndrome of inappropriate antidiuresis (SIAD)-like presentation warranting fluid restriction, according to a recent study.

Bimekizumab safe, effective in moderate-to-severe plaque psoriasis
The high clinical response levels achieved with bimekizumab over 48 weeks persist up to week 96 in patients with moderate-to-severe plaque psoriasis, results of the BE RADIANT phase IIIb trial have shown. In addition, those on secukinumab who switched to bimekizumab have achieved similar responses at 96 weeks.

Durvalumab plus radiotherapy shows promise in unresectable NSCLC
In the treatment of patients with programmed cell death ligand 1 (PD-L1)-positive, unresectable, and locally advanced nonsmall cell lung cancer (NSCLC), the use of durvalumab immunotherapy in combination with curative radiotherapy yields survival gains with tolerable adverse events (AEs), as shown in the results of the phase II DOLPHIN trial.





