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Pyrotinib plus trastuzumab-docetaxel prolongs PFS in breast cancer
Treatment with pyrotinib in combination with trastuzumab and docetaxel (tras/doc) results in longer progression-free survival (PFS) than placebo combined with tras/doc in patients with untreated HER2-positive metastatic breast cancer, a study has shown. In addition, the safely profile of tras/doc plus pyrotinib is manageable.

Machine learning predicts AF in heart failure patients
Use of machine learning (ML) can help pinpoint novel factors that contribute to an increased risk of atrial fibrillation (AF) in non-White patients with heart failure (HF), suggests a study. Specifically, social factors such as living alone may significantly heighten the AF risk.

Does migraine increase the risk of COVID-19 in women?
Older women with a history of migraine need not worry too much about developing COVID-19, with a recent study suggesting that no significant association exists between migraine history and an increased risk of having COVID-19.

Nodal staging before SBRT does not affect survival in early-stage NSCLC
Patients with early-stage nonsmall cell lung cancer (NSCLC) treated with stereotactic body radiation therapy (SBRT) have similar overall survival (OS) regardless of nodal staging, reports a study. In addition, use of SBRT has shown a steady increase over the study period.




