Filters
Treatment with the first-in-class oral nonazole, triterpenoid antifungal ibrexafungerp appears to be efficacious and well-tolerated in patients with recurrent vulvovaginal candidiasis, as shown in the phase III CANDLE study.
A handheld, battery-powered lab-in-tube assay device can deliver accurate tuberculosis (TB) diagnoses in less than an hour, according to a study.
Infants exposed to antiretroviral treatment (ART) regimens containing integrase strand transfer inhibitors (INSTIs) in utero seem to fare as well as their nonexposed peers in terms of neurodevelopment, as reported in a study.
Switching to dolutegravir/lamivudine (DTG/3TC) or continuing bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) showed comparable virologic efficacy through 96 weeks in adults with HIV infection, according to the DYAD observational, open-label extension (OLE) study presented at IDWeek 2025.
New drug applications approved by US FDA as of 16-31 October 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Acute dengue virus (DENV) infection appears to be associated with an increased likelihood of new-onset neurologic events, although the overall increase appears modest, according to a retrospective study from Singapore.
For individuals with persisting COVID-19 symptoms, a 3-month resistance exercise program appears to yield greater improvements in physical function and psychological well-being compared with usual care alone, as shown in a study.
Children hospitalized for viral respiratory diseases carry a significant burden of illness, reports a study.
A recent study has found a low incidence of mediastinitis, a rare complication of neonatal cardiac surgery, at a tertiary referral centre, but mortality is high. Fungal infection is the main predictor of death.
Treatment with oseltamivir in children hospitalized with influenza helps prevent progression into a state requiring ICU admission and shorten the length of hospital stay, as shown in a US-based retrospective study.
