News & Updates

Treatment outcomes for patients with high-risk neuroblastoma in Southeast Asia are poor all in all, but intensified medical and surgical procedures appear effective at improving survival rates, according to a study in Singapore.

Children who have been diagnosed with Wilms tumour (WT) at an older age appear to have worse overall survival (OS), reveals a study.

Induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CCRT) appears promising in its capacity to increase overall survival (OS) among patients with T3-4N0-1 nasopharyngeal carcinoma (NPC) compared with CCRT alone, suggests a recent study in China.

Revumenib, a novel potent, selective oral inhibitor of the menin-KMT2A interaction, demonstrated promising antileukaemic activity in children and adults with highly refractory acute leukaemia with KMT2Ar* or NPM1* mutation, a phase I dose-escalation study finds.

Whatever choice of therapy men with localized prostate cancer may have initially— surgery, radiation, or active monitoring — they would likely have a good 15-year outcome as shown in the ProtecT* trial.

Exposure of senaparib, a highly potent poly-(ADP-ribose) polymerase 1/2 inhibitor and CYP3A4 substrate, is significantly increased when administered along with itraconazole and significantly decreased when taken together with rifampicin, reports a recent study involving healthy male volunteers (HMV) in China.