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Viral load, ART regimen predict mortality in infants born to mothers living with HIV
Several infants born to mothers living with HIV die within 50 weeks, and some of the factors that may contribute to infant death include lower maternal CD4 count, higher viral load, and maternal antiretroviral (ART) regimen, among others, suggests a study presented at CROI 2026.
COVID shots moderately effective against postacute sequelae
COVID-19 vaccination appears to be moderately effective at preventing lingering symptoms following SARS-CoV-2 infection, and this effectiveness may increase with the number of doses administered, according to a meta-analysis.
1HP safe, feasible for tuberculosis prevention in exposed individuals without HIV
Treatment with isoniazid and rifapentine (HP) either for 1 month daily (1HP) or 3 months weekly (3HP) results in high rates of treatment success among people with a positive latent tuberculosis infection test and without HIV infection, a study has shown. The 3HP regimen has slightly lower rates of adverse reactions, but neither exhibits superiority to the other.
ARTISTRY-1 supports switch from complex HIV regimen to a novel single pill
The phase II/III open-label ARTISTRY-1 trial shows that people living with HIV (PWH) may simplify their complex regimen (CR) by switching to a novel daily single-tablet regimen (STR) comprising bictegravir and lenacapavir (BIC+LEN).