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High-dose radiotherapy boosts biochemical control in Gleason 9–10 prostate cancer
In patients with clinically localized Gleason 9–10 prostate cancer, dose-escalated radiotherapy confers better biochemical disease-free survival and prostate cancer-specific mortality than conventional doses, a recent study has found.

Pola-R-CHP triumphs over R-CHOP in improving PFS in DLBCL
The combination of polatuzumab vedotin with rituximab, cyclophosphamide, doxorubicin, and prednisone (pola-R-CHP) demonstrated a significant improvement in progression-free survival (PFS) over the standard-of-care (SoC) regimen of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with previously untreated diffuse large B-cell lymphoma (DLBCL), according to results of the phase III POLARIX study.

Young-onset dementia common in Southeast Asia
Young-onset dementia (YOD), particularly the Alzheimer’s type, occurs with high frequency among Southeast Asians, according to data from a memory clinic cohort in Singapore. Furthermore, YOD patients with higher education and those who have late-onset dementia with moderate-to-severe cerebrovascular disease burden exhibit a steeper and faster decline in global cognition.

Psychosis not uncommon in Parkinson’s disease, signals cognitive decline
A significant presence of psychosis exists among patients with Parkinson’s disease (PD) in Singapore, potentially indicating a more rapid cognitive decline and progression of PD severity, reports a study.




