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5-ASA use in paediatric CD common, deviates from recommended practices
Children with Crohn’s disease (CD) are often treated with 5-aminosalicylate (5-ASA) contrary to guidelines, and this practice is associated with a substantial delay in initiating biologic therapy, according to a study presented at this year’s Crohn's & Colitis Congress.

Does LMWH improve live birth rate in women with inherited thrombophilia and miscarriage history?
The use of low-molecular-weight heparin (LMWH) during pregnancy did not increase the likelihood of live birth compared with standard surveillance in women with inherited thrombophilia who have experienced multiple miscarriages, according to a multinational study presented at ASH 2022.

Modified Atkins diet may be better than keto for childhood drug-resistant epilepsy
Dietary modifications offer short-term benefits in children with drug-resistant epilepsy, but modified Atkins diet appears more tolerable and more likely to reduce the frequency of seizures than ketogenic diet, as shown in a study.

COVID-19 vaccines partially effective against Omicron BA.2 infection in children and adolescents in HK
According to a retrospective, territory-wide, case-based study, the mRNA-based BNT162b2 vaccine and inactivated CZ02 vaccine were partially effective against SARS-CoV-2 infection in children and adolescents during the Omicron BA.2 wave in Hong Kong.

Bionic pancreas better controls glucose levels than standard care in T1D
Insulin delivery via a bionic pancreas better controlled HbA1c levels compared with standard of care (SoC) in patients with type 1 diabetes (T1D), according to a recent multicentre trial from the US.



