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Post-COVID sequelae conditions identified, could help establish definition
Patients diagnosed with COVID-19 could have an increased risk of certain conditions up to 120 days post-diagnosis, a finding which could help establish the definition of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), according to a study presented at CROI 2022.
Neoplastic progression to pancreatic cancer slips by imaging surveillance
Imaging-based surveillance techniques may miss hallmarks of progression in high-risk individuals presenting with high-grade dysplasia or pancreatic cancer, suggesting a need for more sensitive tools, a recent study has found.
Immune-related adverse events portend better prognosis in ICI-treated hepatocellular carcinoma
Among advanced hepatocellular carcinoma patients being treated with immune checkpoint inhibitors (ICIs), the occurrence of multisystem and more severe immune-related adverse events is a favourable signal, being associated with survival advantage, according to a Singapore study.
COVID-19 vaccines less effective in immunocompromised people
Immunocompromised patients, particularly those who had undergone organ transplants, show markedly lower seroconversion rates after vaccination against the coronavirus disease 2019 (COVID-19), according to a recent Singapore meta-analysis.
Selective TYK2 inhibitor safe, works against psoriatic arthritis
Deucravacitinib, a selective TYK2 inhibitor, is well tolerated and appears to produce marked improvements in American College of Rheumatology 20 (ACR20) and other endpoints in the treatment of patients with psoriatic arthritis (PsA), according to the results of a phase II study.