Sisalon

Symptoms of depression including depression accompanied by symptoms of anxiety, in patients w/ or w/o history of mania, obsessive-compulsive disorder (OCD), panic disorder w/ or w/o agoraphobia, PTSD, social phobia (social anxiety disorder), premenstrual dysphoric disorder (PMDD).

Depression & OCD 50 mg/day. Max: 200 mg/day. Panic disorder, PTSD & social phobia 25 mg/day, then increase to 50 mg once daily after 1 wk. Max: 200 mg/day. PMDD 50 mg/day, either daily throughout the menstrual cycle, or limited to the luteal phase of menstrual cycle. Max: 150 mg/day.

May be taken with or without food.

Hypersensitivity. MAOIs & pimozide.

Do not use in combination w/ MAOI or w/in 14 days of discontinuing MAOI. Seizure disorder, unstable epilepsy, switching from SSRIs, antidepressants or anti-obsessional drugs. Hepatic & renal impairment. Suicide.

Diarrhea/loose stool, dry mouth, dyspepsia, abdominal pain, constipation, pancreatitis, nausea, vomiting, sexual dysfunction (principally ejaculatory delay in males), anorexia, increased appetite, hyponatremia, dizziness, somnolence, tremor, coma, convulsions, headache, hypoesthesia, migraine, movement disorders, involuntary muscle contractions, paresthesia, syncope, insomnia, aggressive reaction, agitation, anxiety, depressive symptoms, euphoria, hallucination, decreased libido, paroniria, psychosis, increased sweating, alopecia, angioedema, face edema, periorbital edema, photosensitivity skin reaction, pruritus, purpura, rash, urticaria.

MAOI, pimozide. CNS depressants, alcohol, lithium, phenytoin, sumatriptan, warfarin, diazepam, tolbutamide, cimetidine, propafenone, flecainide, protein-bound drugs.

Antidepressants

N06AB06 - sertraline ; Belongs to the class of selective serotonin reuptake inhibitors. Used in the management of depression.

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