Penem Dosage & Drug Information

Concise Prescribing Info

Contents

Meropenem

Indications/Uses

Listed in Dosage.

Dosage/Direction for Use

Adult Pneumonia, UTI, gynaecological, skin & skin structure infections 500 mg IV 8 hrly. Nosocomial pneumonias, peritonitis, presumed infections in febrile neutropenic patients, septicaemia 1 g IV 8 hrly. Meningitis 2 g 8 hrly. Adjust dose in patients w/ CrCl <51 mL/min. Childn >3 mth-12 yr 10-20 mg/kg 8 hrly depending on type & severity of infection. Meningitis 40 mg/kg 8 hrly. Febrile episodes in neutropenic patients 20 mg/kg 8 hrly.

Contraindications

Hypersensitivity.

Special Precautions

Hepatic disease, history of GI complaints (pseudomembranous colitis has been reported). Pregnancy & lactation. Childn <3 mth.

Adverse Reactions

Local IV inj reactions. Rash, pruritus, urticaria. Abdominal pain, nausea, vomiting, diarrhoea. Reversible thrombocythaemia, eosinophilia, thrombocytopenia, leucopenia & neutropenia. Increase in serum conc of bilirubin, liver enzymes. Headache, paraesthesiae. Oral & vag candidosis.

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Drug Interactions

Probenecid, nephrotoxic drugs, valproic acid.

MIMS Class

Other Beta-Lactams

ATC Classification

J01DH02 - meropenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.

Thai FDA Category

Presentation/Packing

Form

Penem inj 1000 mg

Packing/Price

1's

Form

Penem inj 500 mg

Packing/Price

1's

Penem

meropenem

Manufacturer:

M & H Manufacturing

Distributor:

B L H Trading