Matenol/Matenol MR Dosage & Drug Information

Indications/Uses

Matenol Prophylaxis of angina pectoris. Matenol MR Add-on therapy for symptomatic treatment in adults w/ stable angina pectoris inadequately controlled by or intolerant to 1st-line antianginal therapies. Adjuvant symptomatic treatment of vertigo & tinnitus. Adjuvant treatment of visual disorders of circulatory origin.

Dosage/Direction for Use

Matenol 20 mg tid. Matenol MR Adult & elderly 35 mg bid. Moderate renal impairment (CrCl 30-60 mL/min) 35 mg once daily, preferably in the morning.

Administration

Should be taken with food.

Contraindications

Matenol MR Hypersensitivity. Parkinson disease, parkinsonian symptoms, tremors, restless leg syndrome or other movement disorders. Severe renal impairment (CrCl <30 mL/min).

Special Precautions

Matenol Pregnancy & lactation. Matenol MR Not recommended for acute angina attacks or initial treatment during acute coronary syndrome. Induced gait disturbances &/or hypotension (especially w/ concomitant antihypertensive use); may increase fall. Carefully monitor parkinsonian symptoms. May affect ability to drive & use machines. Moderate renal impairment. Avoid during pregnancy. Not recommended to breastfeed during treatment. Childn <18 yr. Elderly.

Adverse Reactions

Headache. Matenol GI disturbances. Matenol MR Dizziness; pruritus, rash, urtiacaria; abdominal pain, diarrhea, dyspepsia, nausea, vomiting; weakness.

View ADR Reporting Link

Drug Interactions

Matenol Concomitant use w/ MAOIs; nifedipine. Potentiated effects of other anti-anginals.

MIMS Class

Anti-Anginal Drugs

ATC Classification

C01EB15 - trimetazidine ; Belongs to the class of other cardiac preparations.

Thai FDA Category

D

Presentation/Packing

Form

Matenol FC tab 20 mg

Packing/Price

10 × 10's

Form

Matenol MR MR tab 35 mg

Packing/Price

10 × 10's

Matenol/Matenol MR

trimetazidine

Manufacturer:

Unison

Distributor:

Medline

Marketer:

B.Grimm Pharma